1. To spread or daub with a sticky, greasy, or dirty substance. 2. smeared suntan lotion on my face and arms. 3. To stain by or as if by spreading or daubing with a sticky, greasy, or dirty substance. 4. political enemies who smeared his name. 5. To defeat utterly; smash. 6. To be or become stained or dirtied. 7. A mark made by smearing; a spot or blot. 8. A substance to be spread on a surface. 9. A sample, as of blood or bacterial cells, spread on a slide for microscopic examination or on the surface of a culture medium. 10. An attempt to destroy a reputation; vilification or slander.